Overall, V1.8.1 is extremely slow compared to older versions like V1.7.0. It takes a long time to startup, when switching back to it from another window it takes a while to respond, and the top menu lag too (the blue highlight takes a while to respond to options I hover over).
Anything that opens the file explorer, such as to save or open files, also crashes CHITUBOX. It didn't do it before, but now that it does, it's rendered V1.8.0 unusable.
I've also had an experience where sliced files would skip part of a layer for SOME of the supports or model. I haven't made it occur again from my short time using this version, but it HAS happened and its something I've never run into before.
In my experience, all issues above are not present for version 1.7.0.